What most don't like is the lower MPG running E85, AKA FlexFuel. Around here it is still less expensive to run FF over 93. Sure MPG might drop from say 32mpg down to 25mpg but if you calculate, there is a cool app for this called Flex Fuel Calculator. You put in the MPG and price of the FF and the MPG and price of 93 and it will calculate the difference and show you the cost. The difference here between FF and 93, it is still less expensive to use FF.
Plus I like the benefits of it burning cleaner. My used oil analysis all started coming back with improvements once I started mixing in FF into the vehicles. So for my non FF vehicles I usually mix it 40/60, 40% FF and 60% gas.
I have run 100% FF in my 2002 Silverado, it runs great on it but after a full tank it kicks a lean code on both banks. So I just mix it in. I'm considering converting it to FF. Now on our 2011 Acadia, with the 3.6 VVT and direct injection, it will run 100% FF with no codes and it is not a FF vehicle.
I also like the way the exhaust smells. It has a sweeter smell.