I've ran Sea Foam through my C5Z06, Cavalier, S60R, Jetta, and Murano and have never had any issues with fouled plugs. Always had great results.
I do it similar to this. I always did 1/2 a can through the vacuum and 1/2 in the crank case. I let it sit for 15 minutes and drive it around for a while. I always do this when I need an oil change. Maybe drive the car for 100 miles then change the oil. Like Xtreme said it thins out your oil, usually makes it look like chocolate milk, so you don't want to drive too far or put too much stress on it before the oil change.I also used it in many cars never fouled out any plugs key is to drip it in slow do not put a hose into can and let it suck it up full flow you will do damage let it stream in at a slow rate I did 1/2 can in let it sit 15 min. Other half in tank.